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That is, stimulation of CD74 with exogenous MIF could bring about an abnormal inflammatory point out, as MIF is effective at stimulating CXCR2 and CXCR4 receptors As well as CD74. CXCR2 and CXCR4 receptors when activated encourage influx of neutrophils and lymphocytes, respectively (sixty three, sixty four). Fig. 4: Diagram of your human MIF gene
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